The GeneROOT project aims to use ROOT, a data processing framework developed at CERN for the high-energy physics community, to analyse large genomics datasets. The project is run by CERN openlab in collaboration with King’s College London. As well as creating a ‘minimal viable platform’ in 2017, discussions were held throughout the year with the medical community; Maastricht University Hospital, Maastricht University, King’s College London, and SIDRA Medical Centre in Doha, Qatar, will provide initial test use cases for the platform.